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Liu, Wenjin; Lu, Xiaoyong; Meng, Zihui; Isaacs, Lyle (, Organic & Biomolecular Chemistry)The strategic combination of the methylene bridged glycoluril dimer and triptycene skeletons delivers acyclic water soluble hybrid receptor 1 which is analogous to cucurbit[6]uril. The molecular recognition properties of host 1 toward hydrophobic cationic guests are investigated in detail by a combination of 1 H NMR spectroscopy and isothermal titration calorimetry (ITC) studies. The fluorescence emission of 1 can be selectively and efficiently quenched upon the formation of 1·26 and 1·28 complexes.more » « less
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Lu, Xiaoyong; Samanta, Soumen K.; Zavalij, Peter Y.; Isaacs, Lyle (, Angewandte Chemie International Edition)Abstract We report the synthesis and X‐ray crystal structure of a cucurbituril–triptycene chimeric receptor (1). Host1binds to guests typical of CB[6]–CB[8], but also binds to larger guests such as blue box (20) and the Fujita square (22). Intriguingly, the geometries of the1⋅20and1⋅22complexes blur the lines between host and guest in that both components fulfill both roles within each complex. The fluorescence output of1is fully quenched by the formation of complexes with pyridinium‐derived guests.more » « less
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Liu, Wenjin; Lu, Xiaoyong; Xue, Weijian; Samanta, Soumen K.; Zavalij, Peter Y.; Meng, Zihui; Isaacs, Lyle (, Chemistry – A European Journal)
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